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Spermidine Trihydrochloride 98% Powder High Purity Spermidine 3HCl CAS 334-50-9 Industrial Grade Bulk Supply

Other Name

 Spermidine Trihydrochloride

Appearance

White Powder

Specifications

98% 

Price

425-750 USD

MOQ

1KG

Application

Health care

Certificates

HACCP, ISO22000, Kosher, Halal, TÜVRheinland, EU Organic Certificate, USDA, NOP, FDA

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    product details
    Standardized Material

    SPERMIDINE
    TRIHYDROCHLORIDE

    Our Spermidine Trihydrochloride (CAS 334-50-9) is produced through a standardized preparation process, ensuring an assay of ≥98.0% as verified by HPLC analysis. This crystalline salt form offers enhanced chemical stability and formulation compatibility compared to free-base alternatives. Through rigorous quality control, solvent residues are maintained within established regulatory limits, providing a consistent raw material for research-driven nutraceutical and pharmaceutical applications.

    Assay: ≥98.0% (HPLC)
    CAS: 334-50-9
    C7H19N3·3HCl
    Spermidine Trihydrochloride 98%
    Molecular Stability

    Technical Specifications

    Analytical Characterization
    Product Name
    Spermidine Trihydrochloride
    CAS Registry No.
    334-50-9
    Assay (HPLC)
    ≥ 98.0%
    Molecular Identity
    C7H19N3 · 3HCl
    Physical Form
    White Crystalline Powder
    Solubility
    H2O: 50 mg/mL, clear, colorless
    Loss on Drying
    ≤ 1.0%
    Storage Class
    Standard temperature; kept in a dry and cool place

    * This specification sheet is for informational purposes for professional laboratory use and manufacturing. Full compendial testing (USP/EP) data is documented in the Batch Certificate of Analysis.

    Reference Grade

    Technical Core Advantages

    Material characterization & compliance

    Analytical
    Precision

    Every batch undergoes rigorous HPLC analysis to ensure a standardized purity of ≥98.0%. We provide comprehensive documentation including COAs for heavy metals and microbial limits, ensuring total data traceability for biochemical research and high-end manufacturing.

    Enhanced
    Stability

    The crystalline Trihydrochloride form offers superior shelf-stability compared to liquid alternatives. It exhibits low hygroscopicity and high resistance to oxidation at ambient temperatures, minimizing degradation risks during downstream processing and storage.

    Regulatory
    Compliance

    Our production protocols strictly align with international quality standards. We maintain low solvent residues that comply with stringent European and North American regulatory benchmarks, facilitating seamless import clearance and regulatory approval.

    Certificate of Analysis (COA)

    Product Name Spermidine Trihydrochloride Quantity 500 kg
    Batch No. CRSL260407 Test Date 2026-04-08
    Manufacturing Date 2026-04-07 Expiry Date 2028-04-06
    Items Specification Methods Results
    Color White GB1886.244-2016 Conformity
    Form Powder GB1886.244-2016 Conformity
    Assay ≥98% GB1886.244-2016 98.62%
    Loss on Drying ≤5.0 (g/100g) GB1886.244-2016 1.94
    Ash content ≤4.0 (%) GB1886.244-2016 0.10
    Arsenic (as As) ≤2.0 (mg/kg) GB1886.244-2016 Conformity
    Lead (as Pb) ≤5.0 (mg/kg) GB1886.244-2016 Conformity
    Shelf Life 24 months under standard storage, no antioxidant used.
    Package 25 kg/carton outside and double food plastic bags inside.
    Storage Store in a cool, dry place away from Moisture, Light, and Oxygen.

    Mechanism of Technical Function

    Cellular Homeostasis & Regeneration Pathways

    Induction of Autophagy

    As a potent endogenous polyamine, Spermidine acts as a caloric restriction mimetic. It induces cellular autophagy by inhibiting the EP300 acetyltransferase, triggering the degradation and recycling of damaged organelles and misfolded proteins to maintain cellular proteostasis.

    Translation Modulation

    Spermidine is an essential cofactor for the hypusination of eIF5A (Eukaryotic Translation Initiation Factor 5A). This critical post-translational modification is vital for the efficient synthesis of specific proteins required for cell growth and mitochondrial function.

    Genomic Integrity

    Due to its polycationic nature at physiological pH, Spermidine binds to negatively charged DNA and phospholipids. This interaction helps stabilize chromatin structure and provides a molecular shield against oxidative damage induced by reactive oxygen species (ROS).

    Note: The biochemical mechanisms described are based on current peer-reviewed research. This information is intended for technical professionals and researchers only.

    Spermidine 3HCL apply

    Applications & Industries

    Versatile integration in life sciences

    Advanced Nutraceuticals

    • ▪ Cellular health and longevity support formulations (Capsules & Tablets).
    • ▪ Premium multi-ingredient complexes for metabolic homeostasis.
    • ▪ Stable crystalline ingredient for specialized powdered health supplements.

    Nutricosmetic Systems

    • ▪ High-end skin repair serums and anti-aging topical formulations.
    • ▪ Follicle protection and hair density enhancement products.
    • ▪ Regenerative cosmetic additives focusing on cellular renewal.

    Biochemical Research

    • ▪ Reference standard for autophagy-related in vitro studies.
    • ▪ Growth medium additive for high-fidelity cell culture systems.
    • ▪ Molecular biology investigations into polyamine metabolism.

    Pharma Intermediates

    • ▪ Foundational building block for complex organic synthesis.
    • ▪ Starting material for stable hydrochloride-based derivatives.
    • ▪ Precursor for targeted drug delivery system research.

    Frequently Asked Questions

    Technical support & logistics inquiries
    Q1: What is the difference between the Salt form and the Free Base form? +
    Spermidine Trihydrochloride is a stabilized salt form of Spermidine. Compared to the liquid Free Base, which is highly oxidative, corrosive, and unstable, the Trihydrochloride crystalline form offers superior chemical stability, extended shelf-life, and excellent solubility, making it the preferred choice for solid formulations.
    Q2: Does the product require cold chain transportation? +
    Based on stability stress testing, our Spermidine Trihydrochloride remains stable at ambient temperatures. We utilize moisture-proof and light-shielding packaging, so standard international air freight does not require a cold chain. We recommend storage in a cool, dry place upon receipt.
    Q3: Can you provide third-party test reports? +
    In addition to our internal Laboratory COA, we support and cooperate with customers for re-testing of purity, heavy metals, and solvent residues at recognized third-party analytical institutions (such as SGS or Eurofins) upon request.
    Q4: What is the Minimum Order Quantity (MOQ)? +
    As a primary source supplier, we support projects from the early R&D stage. Sample MOQs start as low as 10g, while commercial order MOQs typically start at 1kg.

    Professional Supply Chain & Services

    Certifications

    Quality Certifications

    Verified Organic, ISO, and Non-GMO standards for global compliance.

    OEM Services

    Custom OEM/ODM

    Tailored formulation and branding solutions for your private label.

    Packaging CRS

    Secure Packaging

    Professional grade multi-layer protection for long-distance transit.

    Transport CRS

    Fast Global Delivery

    Efficient logistics network providing reliable air and sea shipping.

    Private Label and Customized Service

    Spermidine Trihydrochloride Powder is wholesale at the absolutely competitive price for business, and you can also get OEM packaging and private label service from us, so that you can retail the Spermidine Trihydrochloride Powder in small package with your logo and design. Furthermore, Spermidine Trihydrochloride Powder can be supplied in powder and tablet form.
    Get private label Red Sweet Potato Powder now!