Meglumine, chemical name 1-deoxy-1-(methylamino)-D-sorbitol. It is an amino sugar extracted from glucose, a white crystalline powder. Almost odorless, slightly sweet, with salty glutinous rice. Meglumine is used as a co-solvent in pharmaceuticals. Meglumine can form salts with some drugs to increase the solubility of the drug. It can also be used as a co-solvent and surfactant for contrast agents.

What's the Function of Meglumine?

Meglumine can increase the contractility of myocardium, and has the effect of strengthening the heart, as well as the effect of expanding peripheral blood vessels and reducing the load of the heart. It is commonly used clinically in coronary heart disease, hypertensive heart disease and other heart failure symptoms, such as chest tightness, shortness of breath, dyspnea, edema of both lower limbs and so on. It can also improve myocardial metabolism, reduce coronary artery resistance and inhibit platelet activity, so it can also be used to treat stable exertional angina and acute myocardial infarction of coronary atherosclerotic heart disease. Combined with the above effects, it can also be used for myocarditis, dilated cardiomyopathy and other diseases. In addition, it can shorten the duration of arrhythmias and regulate the function of sinus node cells. It has the effect of anti arrhythmias. It can be used clinically for the auxiliary treatment of sick sinus syndrome, such as sinus block, slow fast syndrome, ventricular premature beat and other arrhythmias.

What's the Application of Meglumine ?

1.Meglumine is used as a co-solvent in pharmaceuticals. It can form salts with some drugs to increase the solubility of drugs. It can also be used as a co-solvent and surfactant for contrast agents.

2. Meglumine is an organic base. It is mainly used as a pH adjuster and solubilizer in the preparation of soluble salts of iodinated organic acids (used as X-ray contrast agents).

3. Biochemical research