L-Selenomethionine Powder 0.5% Selenium Food Grade CAS 3211-76-5 Organic Selenium Amino Acid
L-SELENOMETHIONINE
POWDER 0.5% (CAS 3211-76-5)
L-Selenomethionine is the selenium-containing structural analog of the essential amino acid L-methionine, in which the sulfur atom is replaced by selenium. It is the predominant chemical form of selenium found naturally in foods such as grains, legumes, and Brazil nuts. This product is a pre-diluted powder containing 0.5% L-selenomethionine on a dicalcium phosphate (DCP) carrier — a standardization practice employed because the pure amino acid delivers selenium at levels far exceeding safe handling and dosing requirements. The powder is white to off-white in appearance and is intended as a bulk raw material for dietary supplement and animal feed premix manufacturers. L-Selenomethionine provides selenium in an amino acid-bound organic form, distinguishing it from inorganic selenium salts such as sodium selenite.
TECHNICAL SPECIFICATIONS
EVIDENCE & CERTIFICATES
1. HPLC-Verified Selenomethionine Identity
Each batch undergoes HPLC analysis against a certified reference standard to confirm the molecular identity of L-selenomethionine, providing analytical traceability unavailable with undefined selenium yeast preparations.
2. ICP-MS Selenium Content Confirmation
Total selenium content is quantified by ICP-MS or AAS after acid digestion to verify the standardized 0.5% concentration (≡ 2,000 ppm elemental Se), ensuring batch-to-batch dosing accuracy.
3. Heavy Metal & Microbial Compliance
Every batch undergoes heavy metal screening (Pb ≤ 5 ppm, As ≤ 2 ppm) and microbial testing, meeting dual-grade (food and feed) safety requirements. Certified under HALAL, ISO 9001, and ISO 22000.
PRODUCT HIGHLIGHTS
Seleno-Amino Acid — Se Analog of L-Methionine
L-Selenomethionine differs from methionine by a single Se-for-S substitution. This makes it the primary organic selenium species in plant and animal foods — chemically distinct from inorganic salts such as sodium selenite (Na₂SeO₃) and sodium selenate (Na₂SeO₄).
0.5% Pre-Dilution on DCP — Safety-Driven Standardization
Pure selenomethionine contains ~40% elemental Se (~400,000 ppm), requiring specialized handling. The 0.5% DCP dilution reduces Se to 2,000 ppm, enabling accurate microgram-scale dosing without concentrated-selenium handling risks.
HPLC-Identifiable Defined Species
As a methionine analog, L-selenomethionine has a defined molecular structure distinguishable from other selenium species by chromatographic retention time — providing analytical traceability unavailable with undefined "selenium yeast" preparations.
DCP Carrier — Premix-Compatible Excipient
Dicalcium phosphate is a standard premix carrier compatible with other vitamin and mineral powders. It provides good flow properties and does not degrade co-formulated micronutrients during storage.
FUNCTIONAL ROLES
1. Organic Selenium Premix Source
Standardized 0.5% raw material for dietary supplement and animal feed premixes requiring selenium fortification at precise, safe dosing levels.
2. Seleno-Amino Acid Ingredient
Provides selenium in an organic, amino acid-bound form — an alternative to inorganic selenium salts in nutritional formulations where organic selenium speciation is required.
3. Feed Selenium Fortification
Used in livestock, poultry, and aquaculture feed premixes where organic selenium sources are specified for animal nutrition programs.
INDUSTRIAL APPLICATIONS
1. Dietary Supplements
Multi-mineral and multi-vitamin/mineral tablets, capsules, and powder formulations with label-declared selenium content for daily nutritional supplementation.
2. Animal Feed Premix
Livestock, poultry, and aquaculture feed premixes where organic selenium sources are specified for animal growth, immunity, and reproduction programs.
3. Food Fortification
Formulated nutritional products, powdered beverages, and fortified foods produced under applicable selenium fortification regulations.
4. Nutraceutical Blends
Multi-nutrient premix blends where precise organic selenium dosing is required alongside other vitamins and minerals in integrated formulations.
TECHNICAL FAQ
Q1: How does L-selenomethionine differ from sodium selenite?
A: L-Selenomethionine is an organic selenium amino acid (C₅H₁₁NO₂Se) — selenium covalently bonded within an amino acid structure. Sodium selenite is an inorganic salt (Na₂SeO₃) — selenium present as the selenite anion. These are fundamentally different chemical classes with distinct metabolic pathways.
Q2: Why is the product diluted to 0.5% rather than sold pure?
A: Pure selenomethionine contains ~40% Se (~400,000 ppm). The 0.5% DCP dilution reduces this to 2,000 ppm, enabling safe microgram-scale dosing. At full concentration, accidental over-addition could exceed safe selenium limits in formulations.
Q3: How is the 0.5% content verified?
A: Total selenium is quantified by ICP-MS or AAS after acid digestion; selenomethionine identity is confirmed by HPLC against a certified reference standard. Both assays are performed on every batch.
Q4: What is the difference between L-selenomethionine and selenium yeast?
A: Selenium yeast is produced by growing yeast in Se-enriched medium, yielding a variable mixture of selenomethionine, selenocysteine, and unidentified Se species without individual quantification. L-Selenomethionine powder contains a single, chemically defined selenium species at a precise concentration, providing batch-to-batch consistency that yeast preparations cannot achieve.





