High Absorption Liposomal Quercetin Powder Sophora Japonica Extract 50% 70% Quercetin Liposome Bulk Supply
LIPOSOMAL
QUERCETIN POWDER (50% / 70%)
Liposomal Quercetin Powder encapsulates high-purity Quercetin (CAS 117-39-5) — one of the most extensively studied dietary flavonols, naturally abundant in onions, apples, and Sophora japonica — within a stable phospholipid bilayer structure. Available at 50% and 70% active loading grades, this ingredient overcomes quercetin's inherently poor water solubility and limited oral bioavailability, transforming it into a water-dispersible, high-bioavailability delivery system for premium immune, cardiovascular, and antioxidant formulations.
TECHNICAL SPECIFICATIONS
LIPOSOMAL DELIVERY PRINCIPLE
Quercetin, despite being one of the most potent dietary polyphenols with well-documented antioxidant and immune-modulating properties, suffers from extremely low aqueous solubility (< 1 µg/mL) and rapid first-pass metabolism — resulting in oral bioavailability typically below 2%. Our liposomal process integrates quercetin into the lipid core of phospholipid vesicles through controlled emulsification and spray-drying.
The resulting liposome mimics the body's natural lipid transport carriers, enabling absorption primarily via the intestinal lymphatic pathway — partially bypassing hepatic first-pass metabolism — while the phospholipid bilayer provides a physical barrier against light, oxygen, and moisture. The final powder combines the handling convenience of a dry ingredient with the water-dispersible performance of a liposomal delivery system.
KEY ADVANTAGES
Dual-Grade Flexibility (50% & 70%)
Two loading grades allow formulators to balance cost-per-active and dosage compactness across different product tiers — from everyday immune support to high-potency therapeutic nutrition.
Water Dispersibility
Converts the near-insoluble quercetin crystal into a readily dispersible powder, enabling stick packs, functional beverages, and effervescent formats previously impossible with standard quercetin.
Oxidation & Light Protection
The phospholipid bilayer shields quercetin from photodegradation and oxidative degradation during manufacturing and shelf storage, preserving its polyphenolic integrity.
Lymphatic Absorption Pathway
Liposomal encapsulation aligns delivery with the body's lipid absorption route, supporting more consistent systemic exposure compared to conventional quercetin powders.
EVIDENCE & LAB VERIFICATION
1. HPLC Active Assay
Every production batch undergoes HPLC analysis to confirm declared Quercetin loading (50% or 70%).
2. DLS Particle Size Analysis
Dynamic light scattering analysis verifies stable liposome formation within the 100nm–300nm range upon rehydration.
3. Encapsulation Efficiency (EE%) Reporting
Batch-typical EE% values (≥ 90%) are reported to confirm genuine encapsulation within the liposome structure.
4. Heavy Metal Screening
Rigorously monitored to comply with global safety standards (Pb ≤ 10 ppm, As ≤ 1 ppm, Cd ≤ 1 ppm, Hg ≤ 0.1 ppm).
FUNCTIONAL ROLES
1. Immune System Modulation Support
Quercetin is widely studied for its role in modulating immune signaling pathways, including mast cell stabilization and cytokine regulation. Liposomal delivery enhances its suitability for seasonal and year-round immune formulations.
2. Cellular Antioxidant Defense Support
As a potent flavonoid antioxidant, quercetin directly scavenges reactive oxygen species (ROS) and supports the body's endogenous antioxidant enzyme systems, including superoxide dismutase (SOD) and glutathione peroxidase (GPx).
3. Cardiovascular Function Support
Quercetin contributes to maintaining healthy vascular endothelial function and normal blood pressure through multiple pathways, making it a cornerstone active in heart-health supplement formulations.
4. Exercise Recovery & Performance Support
Emerging research highlights quercetin's role in supporting mitochondrial biogenesis and reducing exercise-induced oxidative stress, positioning it in the sports nutrition and active lifestyle category.
INDUSTRIAL APPLICATIONS
1. Premium Immune Defense Capsules
Primary application for the 70% grade, delivering high active density for seasonal immune support, respiratory wellness, and daily antioxidant formulations.
2. Functional Beverage Mixes & Stick Packs
Water-dispersible liposomal powder enables quercetin-fortified sachets, effervescent tablets, and functional drink powders — formats previously unattainable with standard quercetin.
3. Sports Nutrition & Recovery Blends
Ideal for post-workout recovery powders, mitochondrial support formulas, and active-lifestyle supplement stacks.
4. Heart Health & Longevity Formulations
Combines naturally with CoQ10, omega-3s, and other cardiovascular actives in comprehensive heart-health and healthy-aging products.
OEM & PACKING
OEM
CERTIFICATES
TRANSPORTATION
PACKAGING
TECHNICAL FAQ
Q1: How does liposomal quercetin compare to standard quercetin powder in formulation value?
A: Standard quercetin has extremely low aqueous solubility (< 1 µg/mL) and oral bioavailability typically below 2%, limiting it to basic capsule formats with uncertain absorption. Liposomal encapsulation converts quercetin into a water-dispersible form while utilizing the lymphatic absorption pathway for more consistent delivery — enabling liquid, stick-pack, and effervescent formats previously impossible.
Q2: Does the 70% loading grade affect dispersion or stability?
A: No — dispersion depends on phospholipid shell integrity, not active loading density. Both 50% and 70% grades pass the same DLS and EE% verification, confirming stable liposome formation upon rehydration.
Q3: What handling precautions are needed during manufacturing?
A: Blend at room temperature; avoid prolonged high-shear mixing. Keep compression forces within standard ranges for tableting. Standard capsule filling is fully compatible. Note: quercetin is sensitive to alkaline pH and metal ions — use purified water and pH-neutral excipients. Store bulk in sealed, nitrogen-flushed containers away from light and heat.