Berberine HCL Berberine Hydrochloride .jpg

High Absorption Liposomal Berberine HCL Powder Berberine Liposome Bulk Supply

Other Name	Liposomal Berberine
Appearance	Yellow Powder
Specifications	50%, 70%
Price	130-180 USD
MOQ	1KG
Application	Health care
Certificates	HACCP, ISO22000, Kosher, Halal, TÜVRheinland, EU Organic Certificate, USDA, NOP, FDA

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product details

What is Berberine HCl Powder?

Berberine HCl Powder (Hydrochloride) is a bioactive alkaloid extracted from traditional medicinal plants such as Berberis aristata (Goldthread) and Phellodendron amurense. Characterized by its brilliant yellow color and intensely bitter taste, Berberine HCl has been a cornerstone of botanical medicine for centuries. Today, it is hailed as a "natural metabolic master switch" due to its unique ability to activate AMPK (adenosine monophosphate-activated protein kinase), which plays a crucial role in regulating blood glucose levels, lipid metabolism, and cardiovascular health.

Nutritional Profile: Berberine (Natural Alkaloid)

Berberine is a powerful bioactive alkaloid extracted from traditional herbs like Goldenseal and Coptis. Often referred to as a "Metabolic Master Switch," it is renowned for its ability to activate AMPK, an enzyme that regulates metabolism. However, standard Berberine HCL faces a significant challenge: extremely poor oral bioavailability (often less than 1%) and potential gastrointestinal side effects at high doses.

Our Liposomal delivery technology bypasses these absorption barriers. By encapsulating Berberine within a phospholipid bilayer, we achieve superior water solubility and facilitate direct intestinal transport. This not only maximizes metabolic impact at lower dosages but also significantly improves digestive comfort, making it the premier choice for professional glucose management.

Superior Water Solubility AMPK Activator Glucose Management Metabolic Support Enhanced GI Comfort

In the functional ingredients market, "liposome" has become synonymous with premium formulation. However, a harsh reality is plaguing global procurement managers: You may be paying liposome prices for "phospholipid mixtures."

What is Liposomal Technology?

Liposomes are an advanced microscopic delivery system. Composed of a phospholipid bilayer, their structure is highly similar to human cell membranes.

High Bioavailability Targeted Release

Core Advantages of Liposomal Berberine

1. Superior Water Solubility

Overcomes the poor solubility of standard Berberine HCL, creating a fully dispersible matrix that enhances interaction with the intestinal lining for better transport.

2. Enhanced Intestinal Permeability

Liposomes protect Berberine from P-glycoprotein efflux—a common "pump" in the gut that pushes berberine back out—resulting in multi-fold higher absorption.

3. Minimized GI Side Effects

High doses of raw berberine can cause cramping. Liposomal encapsulation reduces direct mucosal contact, offering a much gentler experience for the digestive system.

4. Sustained Metabolic Action

By improving the plasma half-life of the alkaloid, liposomes maintain a longer activation of AMPK, supporting steady blood sugar levels throughout the day.

Specifications & Concentration

The percentage concentration (e.g., 20%, 30%, or 50% Berberine) designated for our Liposomal series represents the Active Alkaloid Loading Capacity relative to the total formulation.

Certificate of Analysis

Product Name	Berberine	Quantity	2000 kg
Batch No.	CRSL260312	Test Date	2026-03-13
Manufacturing Date	2026-03-12	Expiry Date	2026-03-11
Items	Specification	Methods	Results
Color	Yellow	GB1886.244-2016	Conformity
Form	Powder	GB1886.244-2016	Conformity
Assay	≥98%	GB1886.244-2016	98.62%
Loss on Drying (g/100g)	≤5.0	GB1886.244-2016	1.94
Ash content（%）	≤4.0	GB1886.244-2016	0.10
Arsenic (as As) (mg/kg)	≤2.0	GB1886.244-2016	Conformity
Lead (as Pb) (mg/kg)	≤5.0	GB1886.244-2016	Conformity
Shelf Life	24 months under the conditions below, no antioxidant used
Package	25 kg/carton outside and double food plastic bags inside.
Storage	Store in a cool, dry place away from Moisture, Light, Oxygen

Function

1. Metabolic Master Switch: Activates the AMPK pathway, shifting cellular energy from storage to active burning, effectively mimicking the metabolic effects of exercise.

2. Glycemic Control: Improves insulin sensitivity and regulates blood sugar levels by slowing carbohydrate absorption and inhibiting hepatic gluconeogenesis.

3. Cardiovascular Health: Supports healthy lipid profiles by lowering LDL (bad cholesterol) and triglycerides through the modulation of PCSK9 expression.

4. Gut Microbiome Support: Acts as a natural selective antimicrobial to balance intestinal flora, reducing systemic inflammation and promoting digestive health.

5. Weight Management: Promotes healthy weight loss by influencing key hormones like insulin and leptin that regulate fat storage.

Application

1. Dietary Supplements: The primary ingredient for metabolic health capsules, tablets, and powders, often standardized to 97% HPLC.

2.Synergistic Formulations: Ideal for combining with Silymarin (to boost absorption), Chromium, or Red Yeast Rice for enhanced efficacy.

3. Functional Foods: Can be integrated into nutrition bars or meal replacements using microencapsulation to mask its natural bitterness.

4. Pharmaceutical API: Used as a high-purity raw material for developing treatments targeting Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease (NAFLD).

5. Animal Nutrition: Utilized in premium pet supplements as a natural, antibiotic-free solution for gut integrity and immune support.

Private Label and Customized Service

Dihydroberberine Powder is wholesale at the absolutely competitive price for business, and you can also get OEM packaging and private label service from us, so that you can retail theDihydroberberine Powder in small package with your logo and design. Furthermore, Dihydroberberine Powder can be supplied in powder and tablet form.

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